I completed my undergraduate degree in Biotechnology
at Sichuan University
in 2008, and came to the Sinclair lab from China in January 2009. My work is
focusing on the gene expression and physiology of Dosophila melanogaster after multiple cold exposures. When exposed to repeated low temperatures, Drosophila
melanogaster females showed an increase in survival, but a
reduction in fecundity. I aim to identify some of the molecular mechanisms that
may underlie this
phenomenon by measuring changes on the gene expression level. I used microarray approach to
differences of gene expression among multiple cold treatment and single cold
treatments on D. melanogaster,
and found several candidate genes repairing cold damage and involved in reproduction.
I then used real time PCR to validate these genes. I’m also interested in
We collected snow fleas from the field during the winter, and measured their
supercooling points. We may use a number of species to do more molecular work
in the future.