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Most Recent Publications:

1.     Kondakova A.N., Ho N.,  Bystrova O.V., Shashkov A.S., Lindner B., Creuzenet C. and Knirel Y.A. (2008). Strutural studies of the O-antigens of Yersinia pseudotuberculosis O:2a and mutants thereof with impaired 6-deoxy-D-manno-heptose biosynthesis pathway. Carbohydrate Research. 343, 13-83-1389.

 

2.     Ho N., Kondakova A.N., Knirel Y.A. and Creuzenet C. (2008). The biosynthesis and biological role of 6-deoxyheptoses in the lipopolysaccharide O-antigen of Yersinia pseudotuberculosis. Molecular Microbiology. 68, 424-447.

 

3.    S. Vijayakumar*, A. Merkx-Jacques*, D.B. Ratnayake, I. Gryski, R.K. Obhi, S. Houle, C. Dozois, and C. Creuzenet  (2006) Cj1121c, a novel UDP-4-keto-6-deoxy-GlcNAc C4 aminotransferase essential for protein glycosylation and virulence in Campylobacter jejuni. J Biol Chem. 281, 27733-27743 . Equal contribution of these two authors.

 

4.     Ishiyama N, Creuzenet C, Miller WL, Demendi M, Anderson EM, Harauz G, Lam JS, Berghuis AM. (2006) Structural studies of FlaA1 from Helicobacter pylori reveal the mechanism for inverting 4,6-dehydratase activity. J Biol Chem. 281, 24489-24495 .

5.     Obhi RK, Creuzenet C. (2005) Biochemical characterization of the Campylobacter jejuni Cj1294, a novel UDP-4-keto-6-deoxy-GlcNAc aminotransferase that generates UDP-4-amino-4,6-dideoxy-GalNAc. J Biol Chem. J Biol Chem. 280, 20902-20908..

6.     Demendi M, Ishiyama N, Lam JS, Berghuis AM, Creuzenet C.(2005) Towards a better understanding of the substrate specificity of the UDP-N-acetylglucosamine C4 epimerase WbpP. Biochem J. 389, 173-180.

7.     Bourke B., Ceponis P., Chiba N., Czinn S., Ferraro R., Fischbach L., Gold B., Hyunh H., Jacobson K., Jones N.L., Koletzko S., Lebel S., Moayyedi P., Ridell R., Sherman P., van Zanten S., Beck I., Best L., Boland M., Bursey F., Chaun H., Cooper G., Craig B., Creuzenet C., Critch J., Govender K., Hassall E., Kaplan A., Keelan M., Noad G., Robertson M., Smith L., Stein M., Taylor D., Walters T., Persaud R., Whitaker S., Woodland R.; Canadian Helicobacter Study Group. (2005) Canadian Helicobacter study group consensus conference: update on the approach to Helicobacter pylori infection in children and adolescents - an evidence-based evaluation. Can. J. Gastroenterology 19, 399-408.

 

8.     Ishiyama N., Creuzenet C., Lam J.S., Berghuis A.M.. (2004) Crystal structure of WbpP, a genuine UDP-N-acetylglucosamine 4-epimerase from Pseudomonas aeruginosa: Substrate specificity in UDP-Hexose 4-epimerases. J. Chem. 279(21):22635-42.
 

9.     Steiner-Mosonyi M, Creuzenet C, Keates RA, Strub BR, Mangroo D. (2004) The Pseudomonas aeruginosa initiation factor IF-2 is responsible for formylation-independent protein initiation in P. aeruginosa. J Biol Chem. 279(50):52262-9.
 

10.  Merkx-Jacques A., Obhi R.K., Bethune G., Creuzenet C. (2004) The Helicobacter pylori flaA1 and wbpB genes control lipopolysaccharide and flagella synthesis/function. J Bacteriol. 186(8):2253-65.
 

11.  Creuzenet C. (2004) Characterization of CJ1293, a new UDP-GlcNAc C6-dehydratases from Campylobacter jejuni. FEBS Letters. 559:136-140.
 

12.  Popot J.L., Berry E.A., Charvolin D., Creuzenet C. et al.. (2003) Amphipols: polymeric surfactants for membrane biology research. Cell Mol Life Sci.. 60(8):1559-74

13.  Creuzenet C., Urbanic R. and Lam J.S. (2002) Structure function studies of two novel UDP-GlcNAc C6-dehydratases / C4 reductases: variation from the SYK dogma. J. Biol. Chem. 277: 26769-26778

14.  Creuzenet C. and Lam J.S. (2001) Topological and functional characterisation of WbpM, an inner-membrane UDP-GlcNAc C6 dehydratase essential for lipopolysaccharide biosynthesis in Pseudomonas aeruginosa. Molecular Microbiology 41(6):1295-310

15.  Creuzenet C., Schurr M., Wakarchuk W., Li J. and Lam J.S. (2000) FlaA1, a new bifunctional UDP-GlcNAc C6 dehydratase / C4 reductase from Helicobacter pylori. J. Biol. Chem. 275: 34873-34880.

16.  Zhao X., Creuzenet C., Belanger M., Egbosimba E., Li J. and Lam J.S. (2000) WbpO, a UDP-N-acetyl D-galactosamine dehydrogenase from Pseudomonas aeruginosa serotype O6. J. Biol. Chem. 275: 33252-33259.

17.  Blankenfeldt W., Giraud M.F., Leonard G., Rahim R., Creuzenet C., Lam J.S. and Naismith J.H. (2000) The purification, crystallisation and preliminary structural characterization of glucose-1-phosphate thymidyltransferase (RmlA), the first enzyme of the dTDP-L-rhamnose synthesis pathway from Pseudomonas aeruginosa. Acta Cryst. D56: 1501-1504.

18.  Creuzenet C., Belanger M., Wakarchuk W. and Lam J.S. (2000) Expression, purification and biochemical characterization of WbpP, a new UDP-GlcNAc C4 epimerase from Pseudomonas aeruginosa serotype O6. J. Biol. Chem. 275: 19060-19067.

19.  Newton T., Creuzenet C. and Mangroo D. (1999) Formylation is not essential for initiation of protein synthesis in all eubacteria. J. Biol. Chem. 274: 22143-22146.

20.  Creuzenet C. and Mangroo D. (1998) Physico-chemical characterization of human Von Ebner's gland protein expressed in E. coli. Implications for its physiological role. Protein Expr. Purif. 14: 254-260.

21.  Thurmond R.L.*, Creuzenet C.*, Reeves P.J. and Khorana G. (1997) Structure and function in rhodopsin. Peptide sequences in the cytoplasmic loops of rhodopsin are intimately involved in interaction with rhodopsin kinase. Proceedings of the National Academy of Science (USA) 94: 1715-1720. * Equal contribution of these two authors.

22. Creuzenet C., Durand C. and Haertlé T. (1997) Interactions of alphas2- and beta-casein signal peptides with DMPC and DMPG liposomes. Peptides. 18: 463-472.

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Last updated: Feb 20, 2008