Selected Recent Publications

Grigg, J.C., J. Cheung, D.E. Heinrichs and M.E. Murphy. 2010. Specificity of staphyloferrin B recognition by the SirA receptor from Staphylococcus aureus. J. Biol. Chem. 285: 34579-34588.

Wyatt, M.A., W. Wang, C.M. Roux, F.C. Beasley, D.E. Heinrichs, P.M. Dunman and N. Magarvey. 2010. Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulence. Science 329: 294-296.

Grigg, J.C., J.D. Cooper, J. Cheung, D.E. Heinrichs and M.E. Murphy. 2010. The Staphylococcus aureus siderophore receptor HtsA undergoes localized conformational changes to enclose staphyloferrin A in an arginine-rich binding pocket. J. Biol. Chem. 285: 11162-11171.

Beasley, F.C. and D.E. Heinrichs. 2010. Siderophore-mediated iron acquistion in the staphylococci. 2010. J. Inorg. Biochem. 104: 282-288.

Torres, V.J., A.S. Attia, W.J. Mason, M.I. Hood, B.D. Corbin, F.C. Beasley, K.L. Anderson, D.L. Stauff, W.H. McDonald, L.J. Zimmerman, D.B. Friedman, D.E. Heinrichs, P.M. Dunman and E.P. Skaar. 2010. Staphylococcus aureus fur regulates the expression of virulence factors that contribute to the pathogenesis of pneumonia. Infect. Imm. 78: 1618-1628.

Cheung, J. F.C. Beasley, S. Liu, G.A. Lajoie and D.E. Heinrichs. 2009. Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus. Mol. Microbiol. 74: 594-608.

Beasley, F.C., E.D. Vines, J.C. Grigg, Q. Zheng, S. Liu, G.A. Lajoie, M.E.P. Murphy and D.E. Heinrichs. 2009. Characterization of staphyloferrin A biosynthetic and transport mutants in Staphylococcus aureus. Mol. Microbiol. 72: 947-963.

Chau, T.A., M.L. McCully, W. Brintnell, G. An, K.J. Kasper, E.D. Vines, P. Kubes, S.M.M. Haeryfar, J.K. McCormick, E. Cairns, D.E. Heinrichs and J. Madrenas. 2009. TLR2 ligands on the staphylococcal cell wall down-regulate superantigen-induced T cell activation and prevent toxic shock syndrome. Nature Medicine. 15: 641-648.

Tiedemann, M.T., N. Muryoi, D.E. Heinrichs and M.J. Stillman. 2008. Iron acquisition by the haem-binding Isd proteins in Staphylococcus aureus: studies of the mechanism using magnetic circular dichroism. Biochemical Society Transactions. 36: 1138-1143.

Muryoi, N., M.T. Tiedemann, M. Pluym, J. Cheung, D.E. Heinrichs and M.J. Stillman. 2008. Demonstration of the iron-regulated surface determinant (Isd) heme transfer pathway in Staphylococcus aureus. Journal of Biological Chemistry. 283: 28125-28136.

Pluym, M.C., N. Muryoi, D.E. Heinrichs and M.J. Stillman. 2008. Heme binding in the NEAT domains of IsdA and IsdC of Staphylococcus aureus. Journal of Inorganic Biochemistry. 102: 480-488.

Pluym, M.C., C.L. Vermeiren, J. Mack, D.E. Heinrichs and M.J. Stillman. 2007. Heme binding properties of Staphylococcus aureus IsdE. Biochemistry. 46: 12777-12787.

Grigg, J.C., C.L. Vermeiren, D.E. Heinrichs and M.E.P. Murphy. 2007. Heme coordination by Staphylococcus aureus IsdE. Journal of Biological Chemistry. 282: 28815-28822.

Grigg, J.C., C.L. Vermeiren, D.E. Heinrichs, M.E.P. Murphy. 2007. Heme recognition by a Staphylococcus aureus NEAT domain. Molecular Microbiology. 63: 139-149.