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- Jha V, Bian C, Xing G, Ling H. (2016). Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase kappa. Nucleic Acids Res.,
Epub 2016 Mar 31. Abstract
- Kirouac KN, Basu AK, Ling H. (2013). Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase. Nucleic Acids Res.,
Epub 2012 Dec 24. Abstract
- Kirouac KN, Ling H. (2011). Pol iota: Shining light on repair of oxidative DNA lesions and mutations. Cell Cycle, Epub 2011 Apr 12. Abstract
- Kirouac KN, Ling H. (2011). Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota. Proc Natl Acad Sci U. S. A., 108(8):3210-5. Epub 2011 Feb 7. Abstract
- Kirouac KN, Suo Z, Ling H. (2011). Structural mechanism of ribonucleotide discrimination by a y-family DNA polymerase. J Mol Biol., 407(3): 382-90. Epub 2011 Feb 3. Abstract
- Chowda-Reddy RV, Sun H, Chen H, Poysa V, Ling H, Gijzen M, Wang A. (2011). Mutations in the P3 protein of Soybean mosaic virus G2 isolates determine virulence on Rsv4-genotype soybean. Mol Plant Microbe Interact, Jan:24(1): 37-43. Abstract
- Wong JH, Brown JA, Suo Z, Blum P, Nohmi T, Ling H. (2010). Structural insight into dynamic bypass of
the major cisplatin-DNA adduct by Y-family polymerase Dpo4. EMBO J., 29(12), 2059-69.
Abstract
- Kirouac KN, Ling H. (2009). Structural basis of error-prone replication and stalling at a thymine base
by human DNA polymerase iota. EMBO J., 28(11), 1644-54.
Abstract
- Xing G, Kirouac K, Shin YJ, Bell SD, Ling H. (2009). Structural insight into recruitment of translesion
DNA polymerase Dpo4 to sliding clamp PCNA. Mol Microbiol., 71(3), 678-91. Epub 2008 Dec 1.
Abstract
- Hlinkova V, Xing G, Bauer J, Shin YJ, Dionne I, Rajashankar KR, Bell SD, Ling H. (2008). Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr D Biol Crystallogr. 64, 941-949 Abstract
- Wong, J. H., Fiala, K., Suo, Z. & Ling, H. (2008). Snapshots of a Y-family DNA polymerase in replication:
substrate-induced conformational transitions and implications for fidelity. J. Mol. Biol., 379 (2), 317-330
Abstract
- Xing, G., Hlinkova, V. & Ling, H. (2007). Purification, crystallization and preliminary diffraction
studies of the Sulfolobus solfataricus PCNA proteins in different oligomeric forms. Crystal Growth & Design. Vol. 7 (11), 2202-2205 Abstract
- Bauer, J., Xing, G., Yagi, H., Sayer, J. M., Jerina, D. M. & Ling, H. (2007). A structural gap in
Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment. PNAS,
104(38), 14905-14910. Abstract
- Fiala, K. A., Brown, J. A., Ling, H., Kshetry, A. K., Zhang, J., Taylor, J. S., Yang, W., & Suo, Z.
(2006). Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase.
J. Mol. Biol. 365, 590-602. Epub 2006 Oct 7. Abstract
- Vaisman A, Ling H, Woodgate R & Yang W. (2005). Fidelity of Dpo4: effect of metal Ions, nucleotide Selection and Pyrophosphorolysis. EMBO J. Vol. 24(17):2957-2967.
Abstract | PDF
- Boudsocq, F., Kokoska, R.J., Plosky, B.S., Vaisman, A., Ling, H., Kunkel, T.A., Yang, W.,
Woodgate, R.(2004). Investigating the role of the little finger domain of Y-family DNA polymerases
in low-fidelity synthesis and translesion replication. J Biol Chem.,2004 Jul 30;279(31), 32932-40.
Abstract | PDF
- Ling, H, Boudsocq, F., Woodgate, R. & Yang, W. (2004).
Snapshots of replication through an abasic lesion: structural basis for base substitutions
and frameshifts. Mol. Cell, Vol. 13, 751-762. Abstract | PDF
- Ling, H, Sayer, J. M., Plosky, B. S., Yagi, H.,
Boudsocq, F., Woodgate, R., Jerina, D. M. & Yang, W. (2004). Crystal
Structure of a Benzo[a]pyrene Diol Epoxide Adduct in a Ternary Complex
with a DNA Polymerase. PNAS, Vol. 101, 2265-2269. Abstract | PDF
- Ling, H., Boudsocq, F., Plosky, B. S., Woodgate,
R., and Yang, W. (2003). Replication of a cis-syn thymine dimer at
atomic resolution. Nature, Vol. 424, 1083-1087. Abstract | PDF
- Boudsocq, F., Ling, H., Yang, W. & Woodgate, R.
(2002). Structure-based interpretation of missense mutations in Y-family
DNA polymerases and their implications for polymerase function and
lesion bypass. DNA Repair, Vol. 1, 343-358. Abstract | PDF
- Ling, H., Boudsocq, F., Woodgate, R. & Yang, W.
(2001). Crystal Structure of a Y-family DNA Polymerase in Action: a
mechanism for error-Prone and lesion bypass replication. Cell,
Vol. 107, 91-102. Abstract | PDF
- Wang J., Ling, H., Yang, W. & Craigie, R.
(2001). Structure of a Two-domain Fragment of HIV-1 Integrase:
Implications for Domain Organization in the Intact Protein. EMBO
J., Vol. 20 (24), 7333-7343. Abstract | PDF
- Ling, H., Pannu, N. S., Boodhoo, A., Armstrong, G.
D., Clark, C. G., Brunton, J. L. & Read, R. J. (2000). A Mutant
Shiga-Like Toxin with Altered Binding Specificity. Structure,
Vol. 8 (3), 253-264. Abstract | PDF
- Kitov, P., Sadowska, J. M., Mulvey, G., Armstrong, G. D.,
Ling, H., Pannu, N. S., Read, R. J. & David R.
Bundle. (2000). Shiga-Like Toxins Are Neutralized by Tailored
Multivalent Carbohydrate Ligands. Nature, Vol. 403,
669-672. Abstract | PDF
- Ling, H., Boodhoo, A., Hazes, B., Armstrong, G. D.,
Brunton, J. L. & Read, R. J. (1998). Structure of Shiga-Like Toxin I
B-Pentamer Complexed with Its Receptor Gb3. Biochemistry, Vol.37
(7), 1777-1788. Abstract | PDF
- Cummings, M. D., Ling, H., H., Armstrong, G. D.,
James L. Brunton & Randy J. Read. (1998). Modeling the
Carbohydrate-Binding Specificity of Pig Edema Toxin.
Biochemsitry, Vol. 37 (7), 1789-1799. Abstract | PDF
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