Welcome to the McCormick Laboratory at  Western University

 
 

Recent Lab News:


Congratulations to Dr. Stacey Xu on her successful PhD defense! Stacey is off to start postdoctoral work with Scott Gray-Owen at the University of Toronto.


















Joseph Zeppa won the Canadian Society of Microbiologists Terry Beveridge Poster Award in the Infection and Immunity section for his presentation entitled “Vaccine approaches targeting colonization by Streptococcus pyogenes” at the joint Canadian Society of Microbiologists/International Unions of Microbiological Societies in Montreal. Congratulations Joe!


Congratulations to Ram, Delfina, and Stacey as their paper was just accepted in Clinical and Experimental Immunology entitled “Th2-polarized invariant natural killer T cells reduce disease severity in intra-abdominal sepsis”.


Congratulations to Stacey, Kevin, Joe and Lorea as their paper was just published ahead of print in Infection and Immunity! Superantigens subvert the neutrophil response to promote abscess formation and enhance Staphylococcus aureus survival in vivo.


Congratulations to Katie, Joe, Adrienne, Stacey, Delfina and Lorea for having their paper now published in PLoS Pathogens! Bacterial superantigens promote acute nasopharyngeal infection by Streptococcus pyogenes in a human MHC class II-dependent manner.


Congratulations to Kelcey’s as well as our former lab members Jen and Pete for publishing their work in PLoS One! Control of established colon cancer xenografts using a novel humanized single chain antibody-streptococcal superantigen fusion protein targeting the 5T4 oncofetal antigen. This paper was recently featured on CTV News and is dedicated to the memory of Alison Look (nee Poon) (1969-2005).


 

Brent Armstrong, B.Sc. Honours, Molecular Biology and Genetics, University of Guelph


Ph.D. Candidate (Sep 2007-)

Dr. Katherine Kasper, B.Sc.Honors, M.Sc., Ph.D., Microbiology and Immunology, Western University


Postdoctoral Associate (March 2013-)

Kelcey Patterson, B.Sc. Honors, Biology, Acadia University


Ph.D. Candidate (Sep 2007-)

Delfina Siroen, B.Sc. Honours, Biochemistry, M.Sc. Biochemistry, Western University


Research Associate (Feb 2009-)

Dr. McCormick is an Associate Professor in the Department of Microbiology and Immunology and a Scientist at the Lawson Health Research Institute.


We are located on UWO campus in the  Sieben's-Drake Research Institute Room 133.


Office phone: (519) 661-3309

Lab phone: (519) 661-2111 x80951

Fax: (519) 661-3499

Email: John McCormick

The Team (summer 2014)

Research in our laboratory has a primary focus on bacterial toxins called “superantigens”. We are interested in the molecular biology and evolution of bacterial superantigens from Streptococcus pyogenes and Staphylococcus aureus and how to engineer superantigens as anti-cancer immunotherapeutics. We also have additional interests in the molecular genetics and biotechnology of probiotic lactobacilli. Our team uses a range of multidisciplinary techniques including bacterial genetics, immunology, protein biochemistry, functional genomics and in vivo models of infectious disease.

Dr. Lorea Baroja, H.B.Sc, Biology, Simon Bolivar University, Doctor of Medical Sciences, Catholic University of Leuven


Research Associate (2011-)

Adrienne Wakabayashi, BMSc Honors, Microbiology and Immunology, Western University


MSc Candidate (Sept 2012-)

Ivor Mahorovic, Undergraduate student (Microbiology and Immunology), Western University


Honors Thesis Student (Sept 2014-)

Joseph Zeppa, BMSc Honors, Microbiology and Immunology, Western University


PhD candidate (Sept 2011-)

William McTavish, Undergraduate student (Microbiology and Immunology), Western University


Honors Thesis Student (Sept 2014-)