Welcome to the McCormick Laboratory at  Western University

 
 

Recent Lab News:


NEW PAPERS PUBLISHED / IN PRESS:


Congratulations to Ram, Delfina, Stacey and Stacey as their paper was just accepted in Clinical and Experimental Immunology entitled “Th2-polarized invariant natural killer T cells reduce disease severity in intra-abdominal sepsis”. We will post a link once the manuscript is online.


Congratulations to Stacey, Kevin, Joe and Lorea as their paper was just published ahead of print in Infection and Immunity! Superantigens subvert the neutrophil response to promote abscess formation and enhance Staphylococcus aureus survival in vivo.


Congratulations to Katie, Joe, Adrienne, Stacey, Delfina and Lorea for having their paper now published in PLoS Pathogens! Bacterial superantigens promote acute nasopharyngeal infection by Streptococcus pyogenes in a human MHC class II-dependent manner.


Congratulations to Kelcey’s as well as our former lab members Jen and Pete for publishing their work in PLoS One! Control of established colon cancer xenografts using a novel humanized single chain antibody-streptococcal superantigen fusion protein targeting the 5T4 oncofetal antigen. This paper is dedicated to the memory of Alison Look (nee Poon) (1969-2005) and was recently featured on CTV News.


May 14 - congratulations to Dr. Ram Anantha who defended his Master’s of Science in Microbiology and Immunology in spectacular fashion!


April 16 - John presented a talk entitled “Streptococcus pyogenes: Human commensal or ‘super’ pathogen” at the 3rd Welcome Trust conference on Exploring Human Host-Microbiome Interactions in Health and Disease at the Welcome Trust Genome Campus in Cambridge, UK. 

Brent Armstrong, B.Sc. Honours, Molecular Biology and Genetics, University of Guelph


Ph.D. Candidate (Sep 2007-)

Dr. Katherine Kasper, B.Sc.Honors, M.Sc., Ph.D., Microbiology and Immunology, Western University


Postdoctoral Associate (March 2013-)

Kelcey Patterson, B.Sc. Honors, Biology, Acadia University


Ph.D. Candidate (Sep 2007-)

Delfina Siroen, B.Sc. Honours, Biochemistry, M.Sc. Biochemistry, Western University


Research Associate (Feb 2009-)

Stacey Xu, BMSc Honors, Microbiology and Immunology, Western University


Ph.D. Candidate (Sept 2009-)

Dr. McCormick is an Associate Professor in the Department of Microbiology and Immunology and a Scientist at the Lawson Health Research Institute.


We are located on UWO campus in the  Sieben's-Drake Research Institute Room 133.


Office phone: (519) 661-3309

Lab phone: (519) 661-2111 x80951

Fax: (519) 661-3499

Email: John McCormick

Kevin Gilmore, Undergraduate student (Anatomy and Cell Biology), Western University


Research Assistant (May 2011-)

The Team:

Research in our laboratory has a primary focus on bacterial toxins called “superantigens”. We are interested in the molecular biology and evolution of bacterial superantigens from Streptococcus pyogenes and Staphylococcus aureus and how to engineer superantigens as anti-cancer immunotherapeutics. We also have additional interests in the molecular genetics and biotechnology of probiotic lactobacilli. Our team uses a range of multidisciplinary techniques including bacterial genetics, immunology, protein biochemistry, functional genomics and in vivo models of infectious disease.

Dr. Lorea Baroja, H.B.Sc, Biology, Simon Bolivar University, Doctor of Medical Sciences, Catholic University of Leuven


Research Associate (2011-)

Dr. Ram Anatha, BScH, MD University of Ottawa, MSc (2014) Microbiology and Immunology, Western University, General Surgery Residency Program (2010-), Western University


Ram recently defended his MSc thesis (co-supervised by Dr. Mansour Haeryfar) and the work is currently under review for publication.  

Adrienne Wakabayashi, BMSc Honors, Microbiology and Immunology, Western University


MSc Candidate (Sept 2012-)

Mathias Kocsis, Undergraduate student (Microbiology and Immunology), Western University


Summer Undergraduate Research Fellowship (SURF) Student (May 2014-)

Ivor Mahorovic, Undergraduate student (Microbiology and Immunology), Western University


Summer Research Assistant (May 2014-)

Joseph Zeppa, BMSc Honors, Microbiology and Immunology, Western University


PhD candidate (Sept 2011-)