Teeter Lab Bio News Research Publications


Matthew G. Teeter Ph.D.
Scientist, Lawson Health Research Institute
Scientist, Robarts Research Institute
Assistant Professor, Medical Biophysics and Surgery
Schulich School of Medicine & Dentistry, Western University
E: matthew.teeter@lhsc.on.ca
T: 519-685-8500 ext 34957 (UH)
T: 519-661-2111 ext 24404 (RRI)
M: 339 Windermere Road, London, ON, N6A 5A5



Photo by Jesica Hurst, Schulich Communications



Bio

Dr. Matthew Teeter leads the basic science research program for the Joint Replacement Institute at London Health Sciences Centre, University Hospital. He is a Scientist at the Lawson Health Research Institute, Scientist at the Robarts Research Institute, and an Assistant Professor in the Departments of Medical Biophysics and Surgery, Schulich School of Medicine & Dentistry at Western University. Dr. Teeter’s research focuses on image-based orthopedic implant design and evaluation. Dr. Teeter received his BSc in Biomedical Science from the University of Guelph and his PhD in Medical Biophysics from Western University, where he was a Graduate Fellow in Musculoskeletal Health Research and Leadership as part of the
Canadian Institutes of Health Research (CIHR) Joint Motion Program. He received national awards at all levels of his graduate and fellowship training from the CIHR. In 2012, he received the Mark Coventry Award for Best Science Paper from the Knee Society, and in 2015 was awarded the John Charles Polanyi Prize in Physiology or Medicine from the Province of Ontario. In 2016 he received an Ontario Early Researcher Award and a CIHR New Investigator Award. In 2018 he received the Early Career Researcher Award in Basic/Clinical Science from the Arthritis Alliance of Canada. Dr. Teeter has taught courses on Scientific Communications in the Medical Biophysics graduate program, and on Research Translation in the Biomedical Engineering graduate program at Western University. Dr. Teeter serves on the boards of the Canadian RSA Network and the International Society for Technology in Arthroplasty (ISTA). In 2019 he served as ISTA's President and brought its annual meeting to Canada for the first time. With surgeon collaborators he has launched multiple companies to commercialization innovations from the Teeter Lab. He was also a co-founder and served as inaugural co-director of the Western Medical Innovation Fellowship program.



News

Some stories related to our work:



Research

Research in the Teeter Lab involves the development and application of medical imaging and sensor technologies to design or evaluate orthopaedic implants and related surgical techniques. In conducting this research our team works in close collaboration with orthopaedic surgeons, imaging scientists, biomedical engineers, life scientists, health economists, and other specialists. Much of the orthopaedic research being accomplished in the City of London is described on Lawson's Orthopaedic Research website. Dr. Teeter and most trainees are members of Western's Bone & Joint Institute and participate in the Collaborative Graduate Program in Musculoskeletal Health. Graduate trainees have been enrolled in the Medical Biophysics, Biomedical Engineering, Kinesiology, Electrical and Computer Engineering, and MSc in Surgery graduate programs. The Lab also hosts undergraduate students as part of summer projects, 3rd or 4th year projects, and co-op terms. The Lab's research has been funded by CIHR, NSERC, The Arthritis Society, the Canadian Orthopaedic Foundation, Ontario Government, and industry, among others. Primary areas of research include:


Implant Retrievals
We oversee Canada’s first and largest implant retrieval laboratory, with over 4,000 failed hip, knee, and shoulder implants that have been explanted from patients. Methods such as micro-CT, visual damage scoring, profilometry, SEM/EDX, and finite element analysis are applied to evaluate the metal and plastic components used in joint replacement implants. 

RSA Wear and Migration
Radiostereometric analysis (RSA) uses calibrated stereo x-rays to quantify the migration and wear of implants over time. We use RSA to evaluate the safety and effectiveness of new implant designs and surgical techniques in patients. We are also part of the Canadian RSA Network, which coordinates multi-centre trials of news implants across the country. 



RSA Kinematics
We also use the RSA system to measure the kinematics of joint replacement implants, comparing implant designs and surgical techniques. From the RSA images we can identify the location of the implanted components, and determine how contact changes as the joint moves.

Additive Manufacturing
In addition to standard 3D printing in plastics, we use selective laser melting (SLM) to 3D print components in metals such as stainless steel, titanium, and cobalt-chrome. We are designing new implant components to address periprosthetic infection and cases of complex revision.



Wearable Sensors
Patient outcome questionnaires have ceiling effects limiting their ability to differentiate subtle differences between patients, and advanced imaging can only be applied in limited clinical trial settings. We are developing wearable sensor technology with machine learning analysis techniques to provide a better, more inexpensive way to evaluate patients with arthritis before and after joint replacement.



Publications

For the most up to date listing of publications, search PubMed for "Teeter MG" or visit Google Scholar.

Lab members also present our research at national and international conferences such as the Canadian Orthopaedic Research Society, Canadian Orthopaedic Association, Canadian Arthroplasty Society, Orthopaedic Research Society, American Academy of Orthopaedic Surgeons, International RSA Meeting, and the International Society for Technology in Arthroplasty.