Dr. Peter B. Stathopulos completed his BSc at the University of Waterloo in Honours Co-operative Biology. He later graduated with an MSc from the University of Western Ontario in Pharmacology and Toxicology, studying the role of L-arginine transport and nitric oxide production in heart failure. His PhD work in Biology at the University of Waterloo interrogated the folding and thermodynamic stability of mutant superoxide dismutases associated with amyotrophic lateral sclerosis. Finally, he completed his post-doctoral training in Structural Biology at the University of Toronto (Medical Biophysics) and the Ontario Cancer Centre, researching the molecular mechanisms underlying store operated calcium entry.

Today, our laboratory in the Department of Physiology and Pharmacology at the University of Western Ontario applies structural biology approaches to reveal the molecular mechanisms regulating calcium signaling processes in health and diseased states including heart disease, cancer and immunodeficiency. We integrate structural biology with a host of biophysical, chemical biology, pharmacology and live cell methodologies to understand the relationship between protein structure and function of calcium signaling proteins integral to life and death processes. Ultimately, we envision using this structure-function data for the identification and/or development of new drugs with the potential to modulate these pathways, maintain health and treat disease.