Dr. Ruth Martin Associate Professor, Graduate Program Chair
Mailing
address
University
of Western Ontario
Elborn
College, Rm 1510
London,
Ontario, Canada
N6B
1H1
Office
Location
Elborn
College, rm 2568
Laboratory
Location
Elborn
College, rm 2528
Phone (office): 519-661-2111 ext. 88186
Phone(lab): 519-661-2111 ext. 80017
Fax: 519-850-2369
E-mail:
remartin@uwo.ca
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Educational Background
1981
B.A. (Hon) Biology/Psychology
Queens
University, Kingston, Canada
1982
M.H.Sc.
Speech-Language Pathology
University
of Toronto, Toronto, Canada
1991
Ph.D. Communicative
Disorders
University
of
Wisconsin-Madison, Wisconsin, U.S.A
1991-1993 Post-Doctoral Fellow, Orofacial
Neurophysiology
University of Toronto, Faculty of
Dentistry,Toronto,Canada
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Members of the Orofacial Neuroscience
Research Team
Rebecca Smith, Research Technician -
rsmith62@uwo.ca
Julie Theurer , PhD candidate -
jasteckl@uwo.ca
Jillian Toogood, MSc candidate -
jtoogoo@uwo.ca
Marlene Fortushnick, MSc candidate - mfortush@uwo.ca
Nesanet Girma, MSc candidate -
nesanetg@uwo.ca
Jennifer Johnston, MSc canidate
- jjohns66@uwo.ca
Research Interests
The
orofacial sensorimotor system supports a number of
fundamental behaviours including swallowing, mastication, and speech
production. Our research is aimed at
understanding how these orofacial behaviours are controlled by the
central
nervous system.
Our current studies combine
functional brain imaging
techniques with orofacial movement analysis in attempts to elucidate
the
relationships between brain activation and the orofacial
function.
Previously we showed that swallowing is associated
with activation of a number of cortical and subcortical structures
including
the lateral pericentral cortex, perisylvian cortex, anterior cingulate
gyrus,
and right insula.
Based on these findings, one current
study is focused on
determining the specialized roles of each of these brain regions in
swallowing
regulation by (i) manipulating attributes of the swallowing task, and
(ii)
comparing swallowing with closely related behaviours such as voluntary
tongue
elevation, and voluntary apnea. A
secondary brain-imaging study is aimed at understanding the
neuropathophysiology of swallowing impairment following hemispheric
stroke, as
well as the mechanisms driving subsequent swallowing recovery.
A.
B.
C.
Figure
A. Blood-Oxygenation-Level-Dependant
(BOLD) response to voluntary saliva swallow. Figure B. Brain activation superimposed on an
inflated brain showing multiple tasks; blue - tongue movement, red -
voluntary saliva swallow, green - finger opposition, yellow -
overlapping swallowing and tongue. Figure C. Modified barium swallow of healthy adult.
Publications
Martin, R.E., MacIntosh, B.J., Smith, R.C.,
Barr, A.M., Stevens,
T.K., Gati, J.S., Menon, R.S. Cerebral areas processing swallowing and
tongue
movement are overlapping and distinct: a functional magnetic resonance
imaging
study. Journal of Neurophysiology. 92:
2428-2443, 2004
Toogood, J.A., Barr, A.M., Stevens, T.K., Gati, J.S.,
Menon, R.S., Martin, R.E. Discrete functional contributions of
cerebral
cortical foci in voluntary swallowing: a functional magnetic resonance
imaging
(fMRI) “go, no-go” study. Experimental
Brain Research, 2004.
Theurer, J., Martin, R.E. Treatment outcomes
in oral cancer: A critical review of effects on swallowing and speech.
Canadian
Journal of Speech Language Pathology and Audiology, 27 (4): 190-201,
2003.
Yao, D.,
Yamamura, K., Narita, N., Martin, R.E., Murray, G.M., Sessle,
B.J.
Neuronal activity patterns in primate primary motor cortex related to
trained
or semiautomatic jaw and tongue movements. Journal of Neurophysiology,
87: 2531-2541,
2002.
Narita, N., Yamamura, K., Yao, D., Martin, R.E.,
Masuda, Y., Sessle, B.J. Effects of reversible bilateral inactivation
of
primate lateral pericentral cortex on mastication. Archives of Oral
Biology,
47: 673-688, 2002.
Yamamura, K.,
Narita, N., Yao, D., Martin, R.E., Masuda, Y.,
Sessle, B.J. Effects of reversible bilateral inactivation of
face
primary motor cortex on mastication and swallowing. Brain Research,
944: 40-55,
2002.
Martin,
R.E., Goodyear, B., Gati, J.S.,
& Menon, R.S .Cerebral cortical representation of automatic and volitional swallowing in
humans. Journal of Neurophysiology, 85:938-950,
2001.
Chen, Y*.,
Barron, J.L., Taves, D.H., Martin, R.E .Computer
measurement of oral movement in
swallowing. Dysphagia, 16:
97-109, 2001.
Martin, R.E.,
Letsos, P., Taves, D.H., Inculet R., Johnston, H., &
Preiksaitis, H.G. Oropharyngeal
dysphagia in esophageal cancer before and following transhiatal
esophagectomy. Dysphagia,
16: 23-31, 2001.
Martin,
R.E., Kemppainen, P., Masuda,
Y., Yao, D., Murray, G.M., & Sessle,B.J.
"Features of cortically evoked swallowing in
the awake primate (macaca fascicularis)." Journal of Neurophysiology,
82:1529-1541, 1999.
Narita, N.,
Yamamura, K., Yao, D., Martin, R.E., & Sessle, B.J.
"Effects
of functional
disruption of the lateral pericentral cerebral cortex on primate
swallowing."Brain
Research, 824, 140-145, 1999.
Martin, R.E., Murray, G.M.,
Kemppainen, P., Masuda, Y., & Sessle, B.J. AFunctional
properties of neurons in the primate tongue primary motor cortex during
swallowing.@ J. Neurophysiology,
78:1516-1530, 1997.
Martin, R.E., Neary, M.A., &
Diamant, N. ADysphagia following
anterior cervical spine surgery". Dysphagia,12:2-8, 1997.
Last revised: 01/09/05