drodenhi@uwo.ca

last update: August 19, 2009

(iDisk and publish.uwo)

My research focuses on the epigenetic regulation of gene expression during tumourigenesis

and development. Errors in DNA methylation patterns and histone modifications can alter gene expression, cause aberrant developmental programs and lead to inappropriate gene expression.

Ongoing research in my lab involves (a) methylation profiling in a variety of cancer-related genes, (b) defining the functional consequences of DNA methylation changes in breast tumourigenesis in general and metastasis in particular, (c) determining how environmental carcinogens alter epigenetic patterns and contribute to tumour formation and (d) defining how environmental pollutants alter epigenetic patterns and compromise embryonic development.

... and an Evolution webpage that will challenge the creationist-minded.