For a full list of our publications: Google Scholar
Rachel E Lackie, Aline S de Miranda, Mei Peng Lim, Vladislav Novikov, Nimrod Madrer, Nadun C Karunatilleke, Benjamin S Rutledge, Stephanie Tullo, Anne Brickenden, Matthew ER Maitland, David Greenberg, Daniel Gallino, Wen Luo, Anoosha Attaran, Irina Shlaifer, Esther Del Cid Pellitero, Caroline Schild-Poulter, Thomas M Durcan, Edward A Fon, Martin Duennwald, Flavio H Beraldo, M Mallar Chakravarty, Timothy J Bussey, Lisa M Saksida, Hermona Soreq, Wing-Yiu Choy, Vania F Prado, Marco AM Prado. (2022). Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo. Acta Neuropathologica, 144(5), 881-910. https://link.springer.com/article/10.1007/s00401-022-02491-8
Benjamin S Rutledge, Wing-Yiu Choy, Martin L Duennwald. (2022). Folding or holding?—Hsp70 and Hsp90 chaperoning of misfolded proteins in neurodegenerative disease. Journal of Biological Chemistry, 298(5). https://www.jbc.org/article/S0021-9258(22)00345-3/fulltext
Carter J Wilson, Wing Yiu Choy, M Karttunen. (2022). AlphaFold2: A Role for Disordered Protein/Region Prediction? International Journal of Molecular Sciences, 23(9), 4591. https://www.mdpi.com/1422-0067/23/9/4591
Vy Ngo, Anne Brickenden, Hansen Liu, Cynthia Yeung, Wing-Yiu Choy, Martin L Duennwald. (2022). A novel yeast model detects Nrf2 and Keap1 interactions with Hsp90. Disease Models & Mechanisms, 15(4), dmm049235. https://journals.biologists.com/dmm/article/15/4/dmm049235/275005/A-novel-yeast-model-detects-Nrf2-and-Keap1
Vy Ngo, Nadun C Karunatilleke, Anne Brickenden, Wing-Yiu Choy, Martin L Duennwald. (2022). Oxidative Stress-Induced Misfolding and Inclusion Formation of Nrf2 and Keap1. Antioxidants, 11(2), 243. https://www.mdpi.com/2076-3921/11/2/243
Ahmed Salem, Carter J Wilson, Benjamin S Rutledge, Allison Dilliott, Sali Farhan, Wing-Yiu Choy, Martin Lothar Duennwald. (2022). Matrin3: Disorder and ALS Pathogenesis. Frontiers in Molecular Biosciences, 8, 794646. https://www.frontiersin.org/articles/10.3389/fmolb.2021.794646/full
Nadun C Karunatilleke, Courtney S Fast, Vy Ngo, Anne Brickenden, Martin L Duennwald, Lars Konermann, Wing-Yiu Choy. (2021). Nrf2, the major regulator of the cellular oxidative stress response, is partially disordered. International Journal of Molecular Sciences, 22(14), 7434. https://www.mdpi.com/1422-0067/22/14/7434
Carter J Wilson, Megan Chang, Mikko Karttunen, Wing-Yiu Choy. (2021). KEAP1 cancer mutants: a large-scale molecular dynamics study of protein stability. International Journal of Molecular Sciences, 22(10), 5408. https://www.mdpi.com/1422-0067/22/10/5408
Megan Chang, Carter J Wilson, Nadun Chanaka Karunatilleke, Mohamed Hesham Moselhy, Mikko Karttunen, Wing-Yiu Choy. (2021). Exploring the conformational landscape of the Neh4 and Neh5 domains of Nrf2 using two different force fields and circular dichroism. Journal of Chemical Theory and Computation, 17(5), 3145-3156. https://pubs.acs.org/doi/abs/10.1021/acs.jctc.0c01243
Rachel E Lackie, Jose Marques-Lopes, Valeriy G Ostapchenko, Sarah Good, Wing-Yiu Choy, Patricija van Oosten-Hawle, Stephen H Pasternak, Vania F Prado, Marco AM Prado. (2020). Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease. Acta neuropathologica communications, 8, 1-19. https://link.springer.com/article/10.1186/s40478-020-01013-5