Particle Technology Research Western

Ying L. Ma, M.E.Sc.

A Research Engineer in the Department of Chemical and Biochemical Engineering, Faculty of Engineering, at the University of Western Ontario. She received her Master degree (Chemical Engineering) in September 1998 from The University of Western Ontario. Most of her previous and current research is in pulmonary drug delivery, ultra-fine powder handling, fine powder coatings on medical dosage forms, and aerosol particles measurement.

Education

M.E.Sc.	Sept. 1996 - May 1998	Department of Chemical and Biochemical Engineering The University of Western Ontario London, Ontario, Canada
M.Sc	Sept. 1987 - July 1990	Department of Chemistry Soochow University Soochow, China
B. Sc.	Sept. 1984 - July 1987	Department of Chemistry Nanjing University Nanjing, China

Professional Experience

Research Engineer	Jun. 2000 - Present	Department of Chemical & Biochemical Engineering The University of Western Ontario London, Ontario, Canada

Research Assistant	Jan. 1999 - May 2000	Department of Chemical Engineering University of Waterloo Waterloo, Canada

Research Chemist	July 1990 - Jun. 1995	Department of Chemistry Suzhou University Soochow, China

Research Interest

	Gas-solid fluidization reactor design and heat transfer study in circulating fluidized bed
	Aerosol particles behaviors and measurement
	Ultrafine powder handling technology, development on new pulmonary drug delivery method, including extrafine drug powder dispensing and dry powder inhaler
	Pharmaceutical process and reactors improvement, including tablets/beads coating, drying and formulation

Projects

	Pulmonary Drug Delivery Research Development of a prototype apparatus to accurately dispense a microgram level medicinal powder (U.S. patent) Development of a novel Dry Powder Inhaler (DPI) with re-chargeable blister packs without compressed air (U.S. patents, applied) Characterization of the fluidized dispensing device and DPIs performance with TSI particle size distribution analyzer, Anderson Cascade Impactor and Next Generation Impactor

	Tablet Coating with dry powder Development of new method for tablets/beads film coating with dry powder materials Design and improvement of the coating formulation and equipment

	Fluidization Heat transfer study in a Co-current and upflow Circulating Fluidized bed.

Selected Publications

Refereed Journal Articles:

Ma Y-L and Zhu J-X. Heat Transfer in the Downer and the Riser of a Circulating Fluidized Bed - A Comparative Study, Chemical Engineering Technology, 24(1), 85-90, 2001.

Ma Y-L and Zhu J-X. Heat transfer between gas-solids suspension and immersed surface in an upflow fluidized bed (riser), Chemical Engineering Science, 55(5), 981-989, 2000.

Zhu J-X, Ma Y-L and Zhang H. Gas-solids contact efficiency in the entrance region of a co-current downflow fluidized bed (downer), Chemical Engineering Research and Design, 77(A2), 151-158, 1999.

Ma Y-L and Zhu J-X. Characterizing gas and solids distributors with heat transfer study in a gas-solids downer reactor, Chemical Engineering Journal, 72(3), 235-244,1999.

Ma Y-L and Zhu J-X. Experimental study of heat transfer in a co-current downflow fluidized bed (downer), Chemical Engineering Science, 54(1), 41-50, 1999.

Book:

	Zhu J-X, Ma Y-L and Luan W-Q, Heat Transfer in Gas-Solid Fluidized Beds, Chapter 6 in Fluidization Engineering Principles, eds. Y Jin, J-X Zhu et al., Tsinghua University Press, Beijing, 2001.

Patents

Zhu J-X, Luo Y, Ma Y-L, Zhang H. Direct Coating Solid Dosage Forms Using Powdered Materials, U.S. Patent, applied, June 2005.

Zhu J-X, Wen J, Ma Y-L and Zhang H. Apparatus for Volumetric Metering of Small Quantity of Powder from Fluidized Beds, U.S. Patent 6684917, February 3, 2004.

Refereed Conference Proceedings:

Zhu J-X, Ma Y-L, "A new breath-activated, excipient-free dry powder inhaler and a rotating fluidized bed powder dispenser for pulmonary drug delivery", Respiratory Drug Delivery X, Florida, April 23-27, 2006.

Zhu J-X, Zhang H, Johnston P M, Ma Y-L, de Lasa HI, Bergougnou M A and Ball J S, "Flow Behavior in the Entrance Region of a Downflow Fluidized Bed", Circulating Fluidized Bed Technology VI, eds. J. Werther, Frankfurt, pp 173-178, 1999.