Latest Publications

2014. Sandieson, L., Hwang, J.T.K., and G.M. Kelly. Redox regulation of canonical Wnt signaling affects extraembryonic endoderm formation. Stem Cells Dev. 23(10): 1037-1049.

2012. Wen, J.W.H., Hwang, J.T.K., and G.M. Kelly. Reactive oxygen species and Wnt signalling crosstalk patterns mouse extraembryonic endoderm. Cell. Signal. 24(12):2337-2348.

2012. Hwang, J.T.K. and G.M. Kelly. GATA6 and FOXA2 regulate Wnt6 expression during extraembryonic endoderm formation. Stem Cells Dev. 21(17):3220-3232.

2010. Sun, Q. and G.M. Kelly. Post-translational modification of CASK leads to its proteasome-dependent degradation. Int. J. Biochem. Cell Biol. 42(1):90-97.

2009. Finkielsztein, A. and G.M. Kelly. Altering PI3K-Akt signalling in zebrafish embryos affects Pten phosphorylation and gastrulation. Biol. Cell. 101:661-678.

2009. Krawetz, R. and G.M. Kelly. Coordinate G-alpha-13 and Wnt6-beta-catenin signaling in F9 embryonal carcinoma cells is required for primitive endoderm differentiation. Biochem & Cell Biol. 87: 567-580.

2008. Kelly, G.M., Saijoh, Y., Finkielsztein, A., and S, Magos. Mouse G-protein gamma3 expression in the developing CNS and neural crest cell derivatives. Int. J. Dev. Biol. 52:1143-50.

2008. Krawetz, R. and G.M. Kelly. Wnt6 induces the specification and epithelialization of F9 embryonal carcinoma cells to primitive endoderm. Cell. Signal. 20:506-517.

2008. Krawetz, R. and G.M. Kelly. Moesin signalling induces F9 teratocarcinoma cells to differentiate into primitive extraembryonic endoderm. Cell. Signal. 20:163-175.

2006. Krawetz, R., MacKenzie, M.J., Sun, Q., Walton, P.A., and G.M. Kelly. G-alpha-13 activation rescues moesin-depletion induced apoptosis in F9 teratocarcinoma cells. Exp. Cell Res. 312:3224-3240.

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Gregory Kelly

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Graduate Opportunities

Over the years my laboratory has been involved in studying several aspects of fish and mouse embryonic development and as such we have generated many spin-off research projects that require further investigation by individuals at the undergraduate, M.Sc., Ph.D, and PDF levels. Many of these projects deal with members of the Wnt signaling pathway that dictate and direct the cell-cell signaling events that pattern the developing embryo. Although our research is focused on the Wnt pathway, we are in no way limited by them. To that end, the lab offers considerable training and we use state-of-the-art molecular, cellular, and biochemical approaches to elucidate a number of diverse biological problems associated with development.

About Me

Dr. Gregory M. Kelly

Professor, Department of Biology
Rm 359, Western Science Centre
1151 Richmond St.
London, Ontario, Canada
N6A 5B7

Phone: 519-661-3121
Fax: 519-661-3935
Email: gkelly@uwo.ca

Curriculum Vitae