The Choy Lab at Western University


Many of the human proteins have been identified to be intrinsically disordered. Even though these proteins lack of a stable structure, they are still biologically functional. Importantly, many of the disordered proteins are associated with cancer, neurodegenerative disorder, and other human diseases. To achieve a better understanding of how disordered proteins function, we use nuclear magnetic resonance (NMR) spectroscopy together with other biophysical techniques to investigate their structure, dynamics, and interactions with other proteins. The results will improve our understanding of this unique class of protein and provide valuable insight into developing therapies to treat the associated diseases. 


Research Interests