Current work
 
Augusto Matarazzo, Robert H.E. Hudson “5-(Acridin-9-ylamino)uracil:  A Self-immolative Nucleobase Modification In Peptide Nucleic Acid” Canadian Journal of Chemistry, submitted June 2013
 
Mark Milne , Pierangelo Gobbo, Nevin McVicar, Mark S. Workentin, Robert Bartha and Robert H. E. Hudson* “Water soluble gold nanoparticles functionalized with gadolinium through Michael addition for use as a MRI contrast agent” submitted May 2013

 

K. Chicas and R.H.E. Hudson, "Expanding the Nucleic Acid Chemist's Toolbox: New Fluorescent Cytidine Analogues" in Fluorescent Analogues of Biomolecular Building Blocks: Design and Applications, Ed.s. Y. Tor and M. Wilhelmmson, John Wiley and Sons, 2012, submitted

 

Mark Milne, Todd K. Stevens, Adam A. Elmehriki, Mojmir Suchy, Robert Bartha, Robert H. E. Hudson Overcoming Biological MT Effects by use of ParaCEST MRI Contrast Agents Possessing Highly Shifted Amide Proton Signals” Proceedings from OctoberCEST, CMMI, 2012 submitted

 

Nevin McVicar, Alex X. Li, Mojmir Suchy, Robert H.E. Hudson, Ravi S. Menon, and Robert Bartha “Mapping In-vivo pH and Temperature Using a PARACEST-MRI Contrast Agent” Proceedings from OctoberCEST, CMMI, 2012 submitted

 

Mojmír Suchý, Alex X. Li, Mark Milne, Robert Bartha and Robert H. E. Hudson “Contrast agents for the detection of NOS enzymatic activity by PARACEST MRI” Proceedings from OctoberCEST, CMMI, 2012 submitted

 

 

Accepted and Published
 
André H. St. Amant, Christopher Engbers and Robert H.E. Hudson* “A Solid-Phase CuAAC Strategy for the Synthesis of PNA Containing Nucleobase Surrogates” Artificial DNA: PNA & XNA, 2013, 4, 4-10.
 

Mojmír Suchý, Robert Bartha and Robert H. E. Hudson* “Click” chemistry toward bis(DOTA-derived) heterometallic complexes:  potential bimodal MRI/PET(SPECT) molecular imaging probes” RSC Advances, 2013, DOI: 10.1039/C3RA23260C
 

Todd K. Stevens, Mark Milne, Adam A. H. Elmehriki, Mojmír Suchý, Robert Bartha, Robert H. E. Hudson* “A DOTAM–based paraCEST agent favoring TSAP geometry for enhanced amide proton chemical shift dispersion and temperature sensitivity” CMMI, 2012, accepted

 

Adam A. H. Elmehriki, Mark Milne, Mojmír Suchý, Robert Bartha and Robert H. E. Hudson* “Complexes of Selected Late Period Lanthanide(III) Cations with DOTAM-Alkyl Ligands: A New Platform for the Development of  PARACEST MRI Contrast Agents” Canadian Journal of Chemistry, 2012, accepted.

 

Alex X. Li, Mojmir Suchy, Robert H.E. Hudson, Ravi S. Menon, Robert Bartha Simultaneous In Vivo Temperature and pH Mapping Using a PARACEST-MRI Contrast Agent” Magnetic Resonance in Medicine, 2012, accepted.

 

Robert Ta, Mojmir Suchy, Alex X. Li, Robert H.E. Hudson, Robert Bartha, Stephen H. Pasternak “A Dual Magnetic Resonance Imaging/Fluorescent Contrast Agent for Cathepsin-D Detection” Contrast Media and Molecular Imaging, 2012, accepted.

 

André H. St Amant, Leslie A. Bean, J. Peter Guthrie and Robert H.E. Hudson “Click Fleximers: A Modular Approach to Expanded Purine Nucleobases” Organic and Biomolecular Chemistry, 2012,  10(32), 6521-6525.

 

Mojmír Suchý, Mark Milne, David W. Dodd, Alex X. Li, Nevin McVicar, Robert Bartha and Robert H. E. Hudson  Polyaza Macrocyclic Ligands Possessing Arginine Pendant Groups for Use in PARACEST”, Contrast Media and Molecular Imaging, 2012,  7(5), 441-449.

 

Mojmír Suchý and Robert H. E. Hudson “Alkylation of Cyclic Amines with Arginine Modified Electrophiles” Synlett, 2012, 23(6), 893-896.

 

Haifeng Song, Piotr M. Diakowski, Robert H. E. Hudson, Heinz-Bernhard Kraatz, “Effect of Ferrocene Position on Charge Transfer in ds-DNA Films” Journal of Inorganic and Organometallic Polymers and Materials, 2012,22(1), 178-182.

 

André H. St. Amant and Robert H.E. HudsonSynthesis and Oligomerization of Fmoc/Boc-Protected PNA Monomers of 2,6-Diaminopurine, 2-Aminopurine and ThymineOrganic and Biomolecular Chemistry, 2012,10(4), 876-881.

 

Adrian G. Torres, Martin M. Fabani, Elena Vigorito, Donna Williams, Naowras Al-Obaidi, Filip Wojciechowski, Robert H. E. Hudson, Oliver Seitz and Michael J. Gait “Structural and mechanistic aspects of microRNA-122 inhibition by anti-miR Peptide Nucleic Acids”  Nucleic Acids Research, 2012, 40(5), 2152-2167.  Doi:10.1093/nar/gkr885.

 

Mark Milne, Kirby Chicas, Alex Li, Robert Barthab and Robert H.E. Hudson ParaCEST MRI Contrast Agents Capable of Derivatization via “Click” ChemistryOrganic and Biomolecular Chemistry, 2012, 10(2), 287-292. DOI:10.1039/C1OB06162C.

 

Mojmír Suchý, Mark Milne, David W. Dodd, Alex X. Li, Nevin McVicar, Robert Bartha and Robert H. E. Hudson “Mono- and Tetraalkyne Modified Ligands and Their Eu3+ Complexes: Utilizing ‘Click’ Chemistry to Expand the Scope of Conjugation Chemistry” European Journal of Organic Chemistry, 2011, 2011(32), 6532-6543.

 

Kalen N. Swanick, David W. Dodd, Jacqueline T. Price, Nathan D. Jones, Robert H.E. Hudson and Zhifeng Ding "Electrogenerated Chemiluminescence of Modified Trizolyldeoxycytidine Analogues in N,N-Dimethylformamide" Physical Chemistry Chemical Physics, 2011, 13(38), 17405-17412.

 

Mojmir Suchy, Adam Elmehriki and Robert H.E. Hudson A Remarkably Simple Protocol for the N-Formylation of Amino Acid Esters and Primary Amines” Organic Letters, 2011, 13(15), 3952-3955.

 

Mark Milne and Robert H.E. Hudson “Contrast agents possessing high temperature sensitivity” Chemical Communications, 2011, 47(32), 9194-9196.

 

Mohamed A.E. Moustafa and Robert H.E. Hudson “An Azo-based PNA Monomer: Synthesis and Spectroscopic studies” Nucleosides, Nucleotides and Nucleic Acids, 2011, 30(9), 740-751.

 

Alexander Wahba, Fereshteh Azizi, Glen Deleavey, Claire Brown, Francis Robert, Marylin Carrier, Anna Kalota, Alan Gewirtz, Jerry Pelletier, Robert Hudson, Masad Damha “Phenylpyrrolocytosine-modified siRNA: Unobtrusive base modification for monitoring activity and cellular trafficking” ACS Chemical Biology, 2011, 6(9), 912-919.

 

David W. Dodd, Sashko Damjanovsk and Robert H.E. Hudson “Peptide Nucleic Acid Pt(II) Conjugates: A Preliminary Study of Antisense Effects in Xenopus laevis Nucleosides, Nucleotides and Nucleic Acids, 2011, 30(4), 257-263.

 

Rebecca Guza, Delshanee Kotandeniya, Kristopher Murphy,Thakshila Dissanayake Chen Lin, George Madalin Giambasu, Rahul R. Lad, Filip Wojciechowski, Shantu Amin, Shana J. Sturla, Robert H.E. Hudson, Darrin M. York, Ryszard Jankowiak, Roger Jones and Natalia Y. Tretyakova “Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA” Nucleic Acids Research, 2011, 39(9), 3988-4006 doi:10.1093/nar/gkq1341.

 

David W. Dodd and Robert H.E. Hudson Hydrogelation abilities of nucleobase-modified cytidines possessing substituted triazolesArtificial DNA, 2010, 1(2), 90-95.  doi: 10.4161/adna.1.2.13975

 

Alex X. Li, Mojmir Suchy, Chunhui Li, Joseph S. Gati, Susan Meakin, Robert H.E. Hudson, Ravi S. Menon and Robert Bartha “ In vivo Detection of MRI-PARACEST Agents in Mouse Brain Tumors at 9.4 Tesla” Magnetic Resonance in Medicine, 2011, 66(1), 67-72. doi: 10.1002/mrm.22772

 

 Mojmír Suchý, Alex X. Li, Robert Bartha, and Robert H. E. Hudson “Synthesis of MRI contrast agents derived from DOTAM-Gly-L-Phe-OH incorporating a disulfide bridge:  conjugation to a cell penetrating peptide and preparation of a dimeric agent” Biological and Medicinal Chemistry Letters, 2010, 20(18), 5521-5526.

 

Mojmír Suchý, Robert Ta, Alex X. Li, Filip Wojciechowski, Stephen H. Pasternak, Robert Bartha and Robert H.E. Hudson A PARACEST-based MRI Probe Metabolized by Cathepsin D: Design, Synthesis and Cellular Uptake StudiesOrganic and Biomolecular Chemistry, 2010, 8, 2560-2566.  

 

Mojmír Suchý, Alex X. Li, Robert Bartha, and Robert H. E. HudsonA bifunctional chelator featuring the DOTAM-Gly-L-Phe-OH structural subunit: en route toward homo- and heterobimetallic lanthanide(III) complexes as PARACEST MRI contrast agents”  Tetrahedron Letters, 2010, 51(7), 1087-1090.

 

Craig K Jones, Alex X. Li, Mojmír Suchý, Robert Hudson*, Ravi S Menon*, Robert Bartha*, “In Vivo Detection of PARACEST Agents With Relaxation Correction” Magnetic Resonance in Medicine, 2010, 63, 1184-1192.

 

David W. Dodd, Kalen N. Swanick, Jacqueline T. Price, Allison L. Brazeau, Zhifeng Ding, Nathan D. Jones, Robert H.E. Hudson  “Blue Fluorescent Cytidine Analogs: convergent synthesis, solid-state and electronic structure, and solvatochromism”, Organic and Biomolecular Chemistry, 2010, 8(3), 663-666.

 

Alexander S. Wahba, Abbasali Esmaeili, Masad J. Damha and Robert H. E. Hudson “A Single-Label Phenylpyrrolocytidine Provides a Molecular Beacon-Like Response Reporting HIV-1 RT RNase H Activity”, Nucleic Acids Research, 2010, 38(3), 1048-1056.

 

Filip Wojciechowski and Robert H.E. Hudson Peptide Nucleic Acid Containing a meta-Substituted Phenylpyrrolocytosine Exhibits a Fluorescence Response and Increased Binding Affinity Towards RNA” Organic Letters, 2009, 11(21), 4878–4881.

 

Jiaxin Hua, David W. Dodd, Robert H. E. Hudson and David R. CoreyCellular localization and allele-selective inhibition of mutant huntingtin protein by peptide nucleic acid oligomers containing the fluorescent nucleobase [bis-o-(aminoethoxy)phenyl]pyrrolocytosine” Bioorganic & Medicinal Chemistry Letters, 2009, 19, 6181-6184.

 

Tsvetan G. Gantchev, Sonia Girouard, David W. Dodd, Filip Wojciechowski, Robert H. E. Hudson and Darel J. Hunting“Gamma-Radiation Induced Interstrand Crosslinks in PNA:DNA  Heteroduplexes” Biochemistry, 2009, 48(29), 7032–7044.

 

Alex X. Li, Mojmir Suchy, Craig K. Jones, Robert H.E. Hudson, Ravi S. Menon and Robert Bartha “Optimized MRI Contrast for On-Resonance Proton Exchange Processes of PARACEST Agents in Biological Systems”, Magnetic Resonance in Medicine, 2009, 62(5), 1282-1291.

 

David Dodd and Robert H.E. Hudson “Intrinsically Fluorescent Base-Discriminating Nucleosides and Analogs”, MiniReviews in Organic Chemistry, 2009, 4, 378-391.

 

Alex X. Li, Robert H.E. Hudson, John Barrett, Craig Jones, Stephen Pasternak and Robert Bartha “Four-Pool Modeling of Proton Exchange Processes in Biological Systems in the Presence of MRI-PARACEST Agents” Magnetic Resonance in Medicine, 2008, 60, 1197–1206.

 

Mojmír Suchý, Robert H. E. Hudson “Synthetic Strategies Toward N-Functionalized Cyclens”, Eur. J. Org. Chem., 2008, 29, 4847-4865.

 

David Dodd, Heather Toews, Michael Trevail, Nathan D. Jones and Robert H.E. Hudson “Synthesis and In-vitro Reactivity of Chiral cis-Dicholoropyridyloxazoline Platinum (II) Complexes” Canadian Journal of Chemistry, 2008, 87(1), 321-327.

 

Filip Wojciechowski and Robert H.E. Hudson A Fmoc/Boc Pseudoisocytosine Monomer for Peptide Nucleic Acid Synthesis Canadian Journal of Chemistry, 2008, 130(38), 12574 - 12575.

 

Filip Wojciechowski and Robert H.E. HudsonFluorescence and Hybridization Properties of Peptide Nucleic Acid Containing a Substituted Phenylpyrrolocytosine Designed to Engage Guanine with an Additional H-Bond” Journal of the American Chemical Society, 2008, 130(38), 12574-12575.

 

Mojmír Suchý, Alex X. Li, Robert Bartha and Robert H.E. Hudson A new synthesis of cystamine modified Eu3+ DOTAM-Gly-Phe-OH: a conjugation ready temperature sensitive MRI contrast agent” Organic & Biomolecular Chemistry, 2008, 6(19), 3588-3596.

 

Mojmír Suchý,Alex X. Li, Robert Bartha and Robert H.E. Hudson “Analogs of Eu3+ DOTAM-Gly-Phe-OH and Tm3+ DOTAM-Gly-Lys-OH: Synthesis and Magnetic Properties of Potential PARACEST MRI Contrast Agents” Bioorganic and Medicinal Chemistry, 2008, 16(11),  6156-6166.

 

Filip Wojciechowski and Robert H.E. Hudson “A Convenient Route to N-[2-(Fmoc)-Aminoethyl]glycine Esters and PNA Oligomerization Using a bis-Boc Nucleobase Protecting Group Strategy” Journal of Organic Chemistry, 2008, 73(10), 3807-3816

 

Alex X. Li, Filip Wojciechowski, Mojmir Suchy, Robert H.E. Hudson, Ravi Menon and Robert Bartha “A Sensitive PARACEST Contrast Agent for In-vivo Temperature MRI: Eu3+-DOTAM-Gly-Phe” Magnetic Resonance in Medicine, 2008, 59, 374-381.

 

David Dodd and Robert H.E. Hudson “Analysis and Purification of Peptide Nucleic Acid by Denaturing Polyacrylamide Gel Electrophoresis” Electrophoresis, 2007, 28(21), 3884-3889.

 

Filip Wojciechowski, Mojmir Suchy, Alex X. Li, Hassan Azab, Robert Bartha and Robert H.E. Hudson “A Robust and Convergent Synthesis of Dipeptide-Cyclen Conjugates as Chelators for Lanthanide Ions:  New Paracest  MRI Agents” Bioconjugate Chemistry, 2007, 18, 1625-1636.

 

Robert H. E. Hudson and Arash Ghorbani Choghamarani “Oligonucleotides Incorporating Structurally Simple 5-Alkynyl-2’-Deoxyuridines Fluorometrically Respond to Hybridization Organic and Biomolecular Chemistry, 2007, 5(12), 1845-1848.

 

Robert H. E. Hudson and Arash Ghorbani-Choghamarani “Selective Fluorometric Detection of Guanosine-Containing Sequences by 6-Phenylpyrrolocytidine in DNA” Synlett, 2007, 6, 870-873.

 

Robert H.E. Hudson, Yuhong Liu and Filip Wojciechowski “Hydrophilic Nucleobase Modifications in Peptide Nucleic Acid:  Synthesis and Properties of PNA Containing 5-Hydroxymethyl- Uracil and Cytosine” Canadian Journal of Chemistry, 2007, 85(4), 302-312.

 

Filip Wojciechowski and Robert H.E. Hudson “Nucleobase Modifications in Peptide Nucleic Acids” Curr. Top. Med. Chem. 2007, 7, 667-679.

 

Benedicte M. Patureau, Robert H.E. Hudson, Masad J. Damha Induction of RNase H activity by arabinose-peptide nucleic acids chimeras” Bioconjugate Chemistry, 2007, 18(2), 421-430.

 

Robert H.E. Hudson and Andrew K. Dambenieks “Synthesis of N1-unsubstituted 5-alkynylcytosine and derivatives thereof” Heterocycles, 2006, 68(7), 1325 - 1328.

 

Robert H.E Hudson and Joanne M. Moszynski “A facile synthesis of fluorophores based on 5-phenylethynyluracils” Synlett, 2006, 18, 2997-3000.

 

Robert H.E. Hudson and Filip Wojciechowski “The detrimental effect of orotic acid substitution in the peptide nucleic acid strand on the stability of PNA2:NA triple helices” Can. J. Chem., 2005, 83(10), 1731-1740.

 

R.H.E. Hudson, M. Goncharenko, A. Wallman, F. Wojciechowski “PNA-directed triple-helix formation by N7-xanthine” SynLett 2005, 9, 1442-1446.

 

R.H.E. Hudson, A.K. Dambenieks, R.D. Viirre “Fluorescent 7-deazapurine derivatives from 5-iodocytosine via a tandem cross-coupling/annulation reaction” Synlett 2004, 13, 2400-2402.

 

R.H.E. Hudson, R.D. Viirre, Y.H. Liu, F. Wojciechowski, A.K. Dambenieks “Chemistry for the synthesis of  Nucleobase-Modified Peptide Nucleic Acid” Pure & Applied Chemistry 2004, 76 (7-8), 1591-1598.

 

L.G. Nikolcheva, C.M. Vogels, R.A. Stefan, H.A. Darwish, S.J. Duffy, R.J Ireland, A. Decken, R.H.E. Hudson, S.A Westcott “Synthesis and in vitro reactivity of cis-dichloro(pyridin-2-ylcarboxaldimine)platinum(II) complexes with DNA” Canadian Journal of Chemistry 2003, 81(4), 269-274.

 

R.D. Viirre and R.H.E. Hudson “A convenient and scalable synthesis of ethyl N-[(2-Boc-amino)ethyl]glycinate and its hydrochloride. Key intermediates for peptide nucleic acid synthesis” Journal of Organic Chemistry 2003, 68 (4), 1630-1632.

 

A.S. King, L.G. Nikolcheva, C.R. Graves, A. Kaminski, C.M. Vogels, R.H.E. Hudson, R.J. Ireland, S.J. Duffy, S.A. Westcott “Synthesis and reactivity of palladium and platinum diimine complexes containing boronate esters” Canadian Journal of Chemistry 2002, 80, 1217-1222.

 

C. Liu, R.H.E. Hudson and N.O. Petersen, “Convergent and sequential synthesis of dendritic, multivalent complexing agents, Synthesis 2002, 10, 1398-1406.

 

 R.H.E. Hudson, G. Li and J. Tse “The Use of Sonogashira Coupling for the Synthesis of Modified Uracil Peptide Nucleic Acid Monomers”, Tetrahedron Letters 2002, 43 (8), 1381-1386.

 

 R.D. Viirre and R.H.E. Hudson "Optimization of a Solid-Phase Synthesis of a PNA Monomer" Organic Letters 2001, 3, 3931-3934.

 

Y.H. Liu and R.H.E. Hudson, “A Sulfonic Acid Analog of Peptide Nucleic Acid”, Synlett 2001, 10, 1626-1628.

 

S. Carriero, R.S. Braich, R.H.E. Hudson, D. Anglin, J.D. Friesen, M.J. Damha “Inhibition of In-vitro Pre-MRNA Splicing in S. Cerevisiae by Branched Oligonucleotides”, Nucleosides and Nucleotides 2001, 20, 873-877.

 

R.H.E. Hudson, S. Robidoux and M.J. Damha, “Divergent Solid-Phase Synthesis of Nucleic Acid Dendrimers”, Tetrahedron Letters 1998, 39, 1299-1302.

 

A.H. Uddin; P.A.E. Piunno; R.H.E. Hudson; M.J. Damha; U.J. Krull,  "An Assay for the Detection of T•AT Triple-Helical DNA Using a Fibre Optic Biosensor", Nucleic Acids Research 1997, 25, 4139-4146

 

R.H.E. Hudson and A.J. Poë, "Systematic CO Dissociation Kinetics of (m2-H)(H)Os3(CO)10L Clusters (L=P-donor Ligand)", Inorganic Chimica Acta, 1997, 259, 257-263.

 

R.H.E. Hudson, A.H. Uddin, M.J. Damha, "Association of Branched Nucleic Acids: Structural and Physicochemical Analysis of Antiparallel T*AT Triple-Helical DNA", Journal of the American Chemical Society 1995, 117, 12470-12477.

 

P.A.E. Piunno, U.J. Krull, R.H.E. Hudson, M.J. Damha, H. Cohen, "Fiber-Optic DNA Sensor for Fluorimetric Nucleic Acid Determination", Analytical Chemistry 1995, 67, 2635-2643.

 

R.H.E. Hudson, A.J. Poë, "Systematic Kinetic Studies of Nucleophile Addition to (m2-H)2Os3(CO)10", Organometallics 1995, 14, 3238-3248.

 

K. Nam, R.H.E. Hudson, K.B. Chapman, K. Ganeshan, M.J. Damha, J.D. Boeke, "Yeast Lariat Debranching Enzyme:  Substrate and Sequence Specificity", Journal of Biological Chemistry 1994, 269, 20613-20621.

 

.A.E. Piunno, U.J. Krull, R.H.E. Hudson, M.J. Damha, H. Cohen, "Fiber-Optic Biosensor for Fluorimetric Detection of DNA Hybridization", Analytical Chimica Acta, 1994, 288, 205-214.

 

R.H.E. Hudson and M.J. Damha, "Nucleic Acid Dendrimers - Novel Biopolymer Structures", Journal of the American Chemical Society, 1993, 115, 2119-2124.

 

M.J. Damha, K. Ganeshan, R.H.E. Hudson, S. Zabarylo, "Solid Phase Synthesis Branched Oligoribo-nucleotides Related to Messenger RNA Splicing Intermediates", Nucleic Acids Research, 1992, 20(24), 6565-6573.

 

R.H.E. Hudson, A.J. Poë, C.N. Sampson, A. Siegal, "Kinetics of Reaction of Hydrogen with [Os3(CO)11NCMe] and [Os3(CO)10NCMe2], Journal of the Chemical Society, Dalton Transactions, 1989, 2235-2240.

 

Papers in refereed conference proceedings (11)

 

Robert H. E. Hudson and Arash Ghorbani Choghamarani “An Improved 6-Substituted Pyrrolocytosine for Selective Fluorimetric Detection of Guanosine-Containing Sequences” Nucleosides, Nucleotides and Nucleic Acids, 2007, 26(6-7), 533-537.

 

Filip Wojciechowski and Robert H. E. Hudson “Synthesis of a Fluorescent PNA Monomer Containing 5-((9H-Fluoren-2-yl)ethynyl)uracil” Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (8-9), 1199-1202.

 

Filip Wojciechowski and Robert H. E. Hudson “Introduction of Chirality into PNA by Replacement of the Achiral Methylene Carbonyl Linkage to the Thymine Nucleobase” Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 26(8-9), 195-1198.

 

R.H.E. Hudson, A.K. Dambenieks and Joanne M. Moszynski “New Fluorescent Nucleobases Derived from 5- Alkynylpyrimidines” Proceedings of SPIE-The International Society for Optical Engineering, (Photonic Applications in Biosensing and Imaging), 2005, 5969, 59690J1-J10.

 

R.H.E. Hudson, A.K. Dambenieks and R.D. Viirre “A Direct Synthesis of Pyrrolocytosine from 5-iodocytosine” Nucleosides, Nucleotides and Nucleic Acids, 2005, 24(5-7), 581-584.

 

 R.H.E. Hudson and F. Wojciechowski “Synthesis and Properties of PNA containing Orotic Acid DerivativesNucleosides, Nucleotides and Nucleic Acids, 2005, 24(5-7), 1123-1126.

 

R.H.E. Hudson, R.D. Viirre, N. McCourt and J. Tse, “Nucleobase Modified Peptide Nucleic Acid”, Nucleosides, Nucleotides and Nucleic Acids, 2003, 5-8, 1029-1033.

 

R.H.E. Hudson and J. Tse, “Towards a Circular Bis-Peptide Nucleic Acid”, Nucleosides, Nucleotides and Nucleic Acids, 2003, 5-8, 1023-1027.

 

Conference proceedings (2)

 

Alexander S. Wahba, Masad J. Damha and Robert H.E. Hudson “RNA containing pyrrolocytidine base analogs: good binding affinity and fluorescence that responds to hybridization” Nucleic Acids Symposium Series 2008, 52, 399-400.

 

Filip Wojciechowski; Robert H.E. Hudson Exceptional Fluorescence and Hybridization Properties of a Phenylpyrrolocytosine in Peptide Nucleic Acid Nucleic Acids Symposium Series, 2008, 52, 401-402.