The Sinclair Lab at UWO
I began my time in the Sinclair lab as a work study student in September 2016. After taking care of fruit flies (and occasionally Colorado potato beetles) for a bit, I decided doing some research of my own would be fun, and Dr. Sinclair was nice enough to agree and take me on through an NSERC USRA.
My current USRA work centres on exploring mechanisms of variation in thiacloprid resistance among Drosophila species. Thiacloprid is a neonicotinoid that is gaining popularity as a commercial insecticide. I will be looking at two possible mechanisms of resistance: increased Cytochrome P450 expression, and single amino acid changes in the Nicotinic Acetylcholine Receptor. This will involve more than enough qPCR and sequencing to keep me happy for the foreseeable future. My work supplements Sirpa Kaunisto’s current efforts on investigating interactions among multiple stressors in Drosophila.