Publications     Total Synthesis     Research Summary for Non-Chemists

List of Publications

Collaborative work is denoted with an asterisk (*). WITHOUT graphical abstracts here.

2015  |  2014  |  2013  |  2012  |  2011  | 2010  |  2009  |  2008  |  2007  |  2006  |  2005  |  2004  |  2003  |  2002  |  2001  |  2000-

2015

  1. Synthesis and reactivity of bis(2,2,2-trifluoroethyl)cyclopropane-1,1-dicarboxylates
    Armstrong, Erin L.; Kerr, Michael A.
    Org. Chem. Front. 2015, 2, 1045-1047. DOI: 10.1039/C5QO00176E
  1. The Synthesis of 5,5-Disubstituted Piperidinones via a Reductive Amination - Lactamization Sequence: The Formal Synthesis of (+/-)-Quebrachamine
    Grover, Huck K.; Kerr, Michael A.
    Synlett 2015, 26, 815-819. DOI: 10.1055/s-0034-1379986
  1. Carbocycles from donor-acceptor cyclopropanes
    Grover, Huck K.; Emmett, Michael R.; Kerr, Michael A.
    Org. Biomol. Chem. 2015, 13, 655-671. DOI: 10.1039/C4OB02117G

2014

  1. Catalyst-Free Tandem Ring-Opening/Click Reaction of Acetylene-Bearing Donor-Acceptor Cyclopropanes
    Flisar, Michelle E.; Emmett, Michael R.; Kerr, Michael A.
    Synlett 2014, 25, 2297-2300. DOI: 10.1055/s-0034-1379107
  1. Advancing the Reactivity of Dimethylcyclopropane-1,1-dicarboxylates via Cross Metathesis
    Vriesen, Matt R.; Grover, Huck K.; Kerr, Michael A.
    Synlett 2014, 25, 428-432. DOI: 10.1055/s-0033-1340460

2013

  1. Scandium Triflate-Catalyzed Nucleophilic Additions to Indolylmethyl Meldrums Acid Derivatives via a Gramine-Type Fragmentation: Synthesis of Substituted Indolemethanes
    Armstrong, Erin L.; Grover, Huck K.; Kerr, Michael A.
    J. Org. Chem. 2013, 78, 10534-10540. DOI: 10.1021/jo4017524
  1. gamma-Substituted Butanolides from Cyclopropane Hemimalonates: An Expedient Synthesis of Natural (R)-Dodecan-4-olide
    Grover, Huck K.; Emmett, Michael R.; Kerr, Michael A.
    Org. Lett. 2013, 15, 4838-4841. DOI: 10.1021/ol402252u

2012

  1. Multicomponent Synthesis of Pyrroles from Cyclopropanes: A One-Pot Palladium(0)-Catalyzed Dehydrocarbonylation/Dehydration
    Humenny, William J.; Kyriacou, Polydoros; Sapeta, Katarina; Karadeolian, Avedis; Kerr, Michael A.
    Angew. Chem. Int. Ed. 2012, 51, 11088-11091. DOI: 10.1002/anie.201206177
  1. Tandem Ring-Opening Decarboxylation of Cyclopropane Hemimalonates with Sodium Azide: A Short Route to gamma-Aminobutyric Acid Esters
    Emmett, Michael R.; Grover, Huck K.; Kerr, Michael A.
    J. Org. Chem. 2012, 77, 6634-6637. DOI: 10.1021/jo3010606

2011

  1. Nucleophilic Ring Opening of Cyclopropane Hemimalonates Using Internal Bronsted Acid Activation
    Emmett, Michael R; Kerr, Michael A.
    Org. Lett 2011, 13, 4180-4183. DOI: 10.1021/ol201486x
  1. Synthesis of Highly Substituted Indoles via Diels-Alder/Plieninger Indolization Sequence: Applications in Total Synthesis
    Sapeta, Katarina; Lebold, Terry P.; Kerr, Michael A.
    Synlett 2011, 11, 1495-1514. DOI: 10.1055/s-0030-1260579
  1. Tandem Cyclopropane Ring-Opening/Conia-ene Reactions of 2-Alkynyl Indoles: A [3+3] Annulative Route to Tetrahydrocarbazoles.
    Grover, Huck K.; Lebold, Terry P.; Kerr, Michael A.
    Org. Lett. 2011, 13, 220-223. DOI: 10.1021/ol102627e

2010

  1. Direct Functionalization of Indoles: Copper-Catalyzed Malonyl Carbenoid Insertions
    Johansen, Michael B.; Kerr, Michael A.
    Org. Lett. 2010, 12, 4956-4959. DOI: 10.1021/ol1020948
  1. Total Synthesis of (+)-Isatisine A
    Avedis Karadeolian; Michael A. Kerr
    J. Org. Chem. 2010, 75, 6830-6841. DOI: 10.1021/jo101209y
  1. Intramolecular Annulations of Donor-Acceptor Cyclopropanes
    Terry P. Lebold; Michael A. Kerr
    Pure Appl. Chem. 2010, 82, 1797-1812. DOI: 10.1351/PAC-CON-09-09-28
  1. Total Synthesis of (+)-Isatisine A
    Avedis Karadeolian; Michael A. Kerr
    Angew. Chem . Int. Ed. 2010, 49, 1133-1135. DOI: 10.1002/anie.200906632

2009

  1. Synthesis of Tetrahydropyrans from Propargyl Alcohols and 1,1-Cyclopropanediesters: A One-Pot Ring-Opening/Conia-Ene Protocol
    Andrew B. Leduc; Terry P. Lebold; Michael A. Kerr
    J. Org. Chem. 2009, 74, 8414-8416. DOI: 10.1021/jo9019122

  1. Heterocycles From Cyclopropanes: Applications in Natural Products Synthesis
    Cheryl A. Carson; Michael A. Kerr
    Chem. Soc. Rev. 2009, 38, 3051-3060. DOI: 10.1039/b901245c
    Featured in the inside front cover. DOI: 10.1039/b920768f

           

  1. Stereodivergent Synthesis of Fused Bicyclo Pyrazolidines: Access to Pyrazolines and Pyrrolidines
    Terry P. Lebold; Michael A. Kerr
    Org. Lett. 2009, 11, 4354-4357. DOI: 10.1021/ol901744e

  1. A Zn(II) Catalyzed Synthesis of Piperidines from Propargyl Amines and Cyclopropanes
    Terry P. Lebold; Andrew B. Leduc; Michael A. Kerr
    Org. Lett. 2009, 11, 3770-3772. DOI: 10.1021/ol901435k

  1. Domino Synthesis of Bridged Bicyclic Tetrahydro-1,2-oxazines: Access to Stereodefined 4-Aminocyclo-hexanols
    Dwayne A. Dias; Michael A. Kerr
    Org. Lett. 2009, 11, 3694-3697. DOI: 10.1021/ol901454y

  1. Synthesis of Cyclohexanes via [3+3] Hexannulation of Cyclopropanes and 2-Chloromethyl Allylsilanes
    Katarina Sapeta; Michael A. Kerr
    Org. Lett. 2009, 11, 2081-2084. DOI: 10.1021/ol900457z

  1. Total Synthesis of FR901483
    Cheryl A. Carson; Michael A. Kerr
    Org. Lett. 2009, 11, 777-779. DOI: 10.1021/ol802870c

2008

  1. Total Synthesis of (−)-Allosecurinine
    Andrew B. Leduc; Michael A. Kerr
    Angew. Chem. Int. Ed. 2008, 47, 7945-7948. DOI: 10.1002/anie.20080325

  1. Expedient Synthesis of Pyrrolo[1,2-a]indoles: Preparation of the Core of Yuremamine
    Michael B. Johansen; Michael A. Kerr
    Org. Lett. 2008, 10, 3497-3500. DOI: 10.1021/ol8012777

  1. Total Synthesis of (±)-Mersicarpine
    Jakob Magolan; Cheryl A. Carson; Michael A. Kerr
    Org. Lett. 2008, 10, 1437-1440. DOI: 10.1021/ol800259s

  1. A Stereodivergent Methodology for the Synthesis of Complex Homochiral Pyrrolidines
    Stephen K. Jackson; Avedis Karadeolian; Alex B. Driega; Michael A. Kerr
    J. Am. Chem. Soc. 2008, 130, 4196-4201. DOI: 10.1021/ja710289k

  1. Total Synthesis of Clausamines A-C and Clausevatine D
    Terry P. Lebold; Michael A. Kerr
    Org. Lett. 2008, 10, 997-1000. DOI: 10.1021/ol703085f

  1. (*) Efficient Synthesis of Isoxazolidine-Tethered Monolayer-Protected Gold Nanoparticles (MPGNs) via 1,3-Dipolar Cycloadditions under High-Pressure Conditions
    Jun Zhu; Brandon M. Lines; Michael D. Ganton; Michael A. Kerr; Mark S. Workentin
    J. Org. Chem. 2008, 73, 1099-1105. DOI: 10.1021/jo702398r

  1. The Reaction of Nitrones with Cyclopropanes: A Convenient Preparation of Tetrahydro-1,2-oxazines
    Cheryl A. Carson; Ian S. Young; Michael A. Kerr
    Synthesis, 2008, 3, 485-489. DOI: 10.1055/s-2007-990864

2007

  1. Examination of a Homo-[3+2]-Dipolar Cycloaddition: Mechanistic Insight into Regio- and Diastereoselectivity
    Avedis Karadeolian; Michael A. Kerr
    J. Org. Chem. 2007, 72, 10251-10253. DOI: 10.1021/jo702073w

  1. The Reaction of Nitrones With Homochiral Cyclopropanes
    Katarina Sapeta; Michael A. Kerr
    J. Org. Chem. 2007, 72, 8597-8599. DOI: 10.1021/jo701606u

  1. Concise Biomimetic Total Synthesis of Both Antipodes of Balasubramide
    Michael B. Johansen; Andrew B. Leduc; Michael A. Kerr
    Synlett, 2007, 16, 2593-2595. DOI: 10.1055/s-2007-986670

  1. (*) Chemical Modification of Monolayer-Protected Gold Nanoparticles Using Hyperbaric Conditions
    Jun Zhu; Michael D. Ganton; Michael A. Kerr; Mark S. Workentin
    J. Am. Chem. Soc. 2007, 129, 4904-4905. DOI: 10.1021/ja070828m

  1. Total Synthesis of Eustifolines A-D and Glycomaurrol via a Divergent Diels-Alder Strategy
    Terry P. Lebold; Michael A. Kerr
    Org. Lett. 2007, 9, 1883-1886. DOI: 10.1021/ol070381m

  1. Total Synthesis of (±)-Herbindole A, (±)-Herbindole B, and (±)-cis-Trikentrin A
    Stephen K. Jackson; Michael A. Kerr
    J. Org. Chem. 2007, 72, 1405-1411. DOI: 10.1021/jo062350v

  1. Total Synthesis of (+)-Nakadomarin
    Ian S. Young; Michael A. Kerr
    J. Am. Chem. Soc. 2007, 129, 1465-1469. DOI: 10.1021/ja068047t

  1. Aryl Amidation Routes to Dihydropyrrolo [3,2-e]indoles and Pyrrolo[3,2-f]tetrahydro-quinolines: The Total Synthesis of the (±)-CC-1065 CPI Subunit
    Michael D. Ganton; Michael A. Kerr
    J. Org. Chem. 2007, 72, 574-582. DOI: 10.1021/jo062064j

  1. Total Synthesis of (±)-Decursivine
    Andrew B. Leduc; Michael A. Kerr
    Eur. J. Org. Chem. 2007, 2, 237-240. DOI: 10.1002/ejoc.200600922

2006

  1. Total Synthesis of (+)-Phyllantidine
    Cheryl A. Carson; Michael A. Kerr
    Angew. Chem. Int. Ed. 2006, 45, 6560-6563. DOI: 10.1002/anie.200602569

  1. Expanding the Scope of Mn(OAc)3-Mediated Cyclizations: Synthesis of the Tetracyclic Core of Tronocarpine
    Jakob Magolan; Michael A. Kerr
    Org. Lett. 2006, 8, 4561-4564. DOI: 10.1021/ol061698+

  1. Synthesis and Cross-Coupling Reactions of 7-Azaindoles via a New Donor-Acceptor Cyclopropane
    Xiaomei Zheng; MIchael A. Kerr
    Org. Lett. 2006, 8, 3777-3779. DOI: 10.1021/ol061379i

  1. Synthesis of the Western Half of the Lolicines and the Lolitrems
    Dylan B. England; Jakob Magolan; Michael A. Kerr
    Org. Lett. 2006, 8, 2209-2212. DOI: 10.1021/ol060338j

  1. The Nicholas-type Activation of Cyclopropanes Toward Reactions with Nitrones in the Homo-[3+2]-Dipolar Cycloaddition
    Terry P. Lebold; Cheryl A. Carson; Michael A. Kerr
    Synlett, 2006, 3, 364-368. DOI: 10.1055/s-2006-926240

2005

  1. (*) The Mechanism of 1,3-Dipolar Cycloaddition Reactions of Cyclopropanes and Nitrones - A Theoretical Study
    Duangporn Wanapun; Kari Ann Van Gorp; Nick J. Mosey; Michael A. Kerr; Tom K. Woo
    Can. J. Chem. 2005, 83, 1752-1767. DOI: 10.1139/v05-182
  1. A Domino Amidation Route to Indolines and Indoles: Rapid Syntheses of Anhydrolycorinone, Hippadine, Oxoassoanine, and Pratosine
    Michael D. Ganton; Michael A. Kerr
    Org. Lett. 2005, 7, 4777-4779. DOI: 10.1021/ol052086c

  1. Diastereoselective Synthesis of Pyrrolidines via the Yb(OTf)3 Catalyzed Three-Component Reaction of Aldehydes, Amines, and 1,1-Cyclopropanediesters
    Cheryl A. Carson; Michael. A. Kerr
    J. Org. Chem. 2005, 70, 8242-8244. DOI: 10.1021/jo0512251

  1. Synthesis and Cross-Coupling Reactions of Substituted 5-Triflyloxyindoles
    Dylan B. England; Michael A. Kerr
    J. Org. Chem. 2005, 70, 6519-6522. DOI: 10.1021/jo050706h

  1. Total Synthesis of (±)-Herbindole B and (±)-cis-Trikentrin B
    Stephen K. Jackson; Scott C. Banfield; Michael A. Kerr
    Org. Lett. 2005, 7, 1215-1218. DOI: 10.1021/ol047498k

  1. Diastereoselective Synthesis of Pyrrolidines Using a Nitrone/Cyclopropane Cycloaddition: Synthesis of the Tetracyclic Core of Nakadomarin A
    Ian S. Young; Justin L. Williams; Michael A. Kerr
    Org. Lett. 2005, 7, 953-955. DOI: 10.1021/ol0501018

2004

  1. Magnesium Iodide Promoted Reactions of Nitrones with Cyclopropanes: A Synthesis of Tetrahydro-1,2-oxazines
    Michael D. Ganton; Michael A. Kerr
    J. Org. Chem. 2004, 69, 8554-8557. DOI: 10.1021/jo048768f

  1. Preparation of Tetrahydrooxazines by the Lewis Acid-Catalyzed Cycloaddition of Nitrones with Cyclopropanes
    Michael A. Kerr; Ian S. Young
    PCT Int. Appl. 2004, 107 pp.
  1. The Diels-Alder Reactions of Quinone Imine Ketals
    Scott C. Banfield; Michael A Kerr
    Can. J. Chem. 2004, 82, 131-138. DOI: 10.1139/v03-188
  1. Three-Component Homo-[3+2]-Dipolar Cycloaddition. A Diversity-Oriented Synthesis of Tetrahydro-1,2-oxazines and FR900482 Skeletal Congeners
    Ian S. Young; Michael A. Kerr
    Org. Lett. 2004, 6, 139-141. DOI: 10.1021/ol0362919

2003

  1. The Total Synthesis of (+)-Hapalindole Q by an Organomediated Diels-Alder Reaction
    Aaron C. Kinsman; Michael A. Kerr
    J. Am. Chem. Soc. 2003, 125, 14120-14125. DOI: 10.1021/ja036191y

  1. A Homo-[3+2]-Dipolar Cycloaddition: The Reaction of Nitrones with Cyclopropanes
    Ian S. Young; Michael A. Kerr
    Angew. Chem. Int. Ed. 2003, 42, 3023-3026. DOI: 10.1002/anie.200351573

  1. Diels-Alder Reactions of 4-Alkoxy-4-alkylcyclohexa-2,5-dienimines: Synthesis of 5-Alkylindoles
    Peter V. Zawada; Scott C. Banfield; Michael A. Kerr
    Synlett, 2003, 7, 971-974. DOI: 10.1055/s-2003-39306

2002

  1. Convenient Preparation of Indolylmalonates via Carbenoid Insertion
    Romelo Gibe; Michael A. Kerr
    J. Org. Chem. 2002, 67, 6247-6249. DOI: 10.1021/jo025851z

  1. The Reactions of 3-Alkylindoles with Cyclopropanes: An Unusual Rearrangement Leading to 2,3-Disubstitution
    Dylan B. England; Tom K. Woo; Michael A. Kerr
    Can. J. Chem. 2002, 80, 992-998. DOI: 10.1139/v02-125

2001

  1. The Diels-Alder Reactions of Quinone Imine Ketals: A Versatile Synthesis of Highly Substituted 5-Methoxyindoles
    Scott C. Banfield; Dylan B. England; Michael A. Kerr
    Org. Lett. 2001, 3, 3325-3327. DOI: 10.1021/ol016562k

  1. Total Synthesis of (±)-Hapalindole Q
    Aaron C. Kinsman; Michael A. Kerr
    Org. Lett. 2001, 3, 3189-3191. DOI: 10.1021/ol0165138

  1. Cyclopentannulation of 3-Alkylindoles: Synthesis of a Tetracyclic Subunit of the Kopsane Alkaloids
    Dylan B. England; Timothy D. O. Kuss, Ryan G. Keddy; Michael A. Kerr
    J. Org. Chem. 2001, 66, 4704-4709. DOI: 10.1021/jo015643r

  1. The Diels-Alder Reactions of Quinone Imine Ketals: A Synthesis of the Ergot Skeleton
    Scott C. Banfield; Michael A. Kerr
    Synlett, 2001, 3, 436-438. DOI: 10.1055/s-2001-11408
  1. A Convenient Preparation of 4-Iodoindoles from indoles: Application to the Chemical Synthesis of Hapalindole Alkaloids
    Martyn A. Brown; Michael A. Kerr, Tetrahedron Lett. 2001, 42, 983-985. DOI: 10.1016/S0040-4039(00)02194-8

2000-

  1. Highly Selective Diels-Alder Reactions of Dienophiles with 1,3-Cyclohexadiene Mediated by Yb(OTf)3.2H2O and Ultrahigh Pressures
    Aaron C. Kinsman; Michael A. Kerr
    Org. Lett. 2000, 2, 3517-3520. DOI: 10.1021/ol0065773

  1. A "One-Pot" Procedure for the Oxidative Conversion of Alkyl Halides and Tosylates to N,N-Dimethylhydrazones
    I. C. Barrett; M. A. Kerr, Synlett, 2000, 11, 1673-1675. DOI: 10.1055/s-2000-7938
  1. The Facile Preparation of Hydrazones by the Treatment of Azides with Hydrazines Catalyzed by FeCl3.6H2O
    I. C. Barrett; J. D. Langille; M. A. Kerr, J. Org. Chem. 2000, 65, 6268-6269. DOI: 10.1021/jo000708w
  1. The Annulation of 3-Alkylindoles with 1,1-Cyclopropanediesters
    M. A. Kerr; R. G. Keddy, Tetrahedron Lett. 1999, 40, 5671-5675. DOI: 10.1016/S0040-4039(99)01107-7
  1. The High-Pressure SnAr Reaction of N-p-Fluorobenzyl-2-chlorobenzimidazole with Amines; An Application to the Synthesis of Norastemizole and Analogues
    I. C. Barrett; M. A. Kerr, Tetrahedron Lett. 1999, 40, 2439-2442. DOI: 10.1016/S0040-4039(99)00290-7
  1. The Ultra High Pressure Conjugate Addition of Indoles to Electron Deficient Olefins
    P. E. Harrington; M. A. Kerr, Can. J. Chem. 1998, 76, 1256-1265. DOI: 10.1139/cjc-76-9-1256
  1. The High Pressure Reaction of Cyclopropanes with Indoles Catalyzed by Ytterbium Triflate
    P. E. Harrington; M. A. Kerr, Tetrahedron Lett. 1997, 38, 5949-5952. DOI: 10.1016/S0040-4039(97)01351-8
  1. Anionic Homologous Fries Rearrangement of O-(2-Methylaryl)Carbamates - A Regiospecific Route to Benzo[B]Furan-2(3H)-ones Including an Unnamed Metabolite From Helenium Species
    Miah, M. A. J.; Chaddopadhyay, S.; Tsukazaki, M.; Wicki, M.; Nguen, T.; Coelho, A. L.; Kerr, M.; Snieckus, V. Synlett, 1997, 7, 839-841. DOI: 10.1055/s-1997-5743
  1. The Reaction of Indoles with Electron Deficient Olefins Catalyzed by Yb(OTf)3.3H2O
    P. E. Harrington; M. A. Kerr, Synlett, 1996, 11, 1047-1048. DOI: 10.1055/s-1996-5685
  1. The High Pressure Diels-Alder Reactions of Quinone-mono-Ketals
    E. R. Jarvo; S. R. Boothroyd; M. A. Kerr, Synlett, 1996, 9, 897-899. DOI: 10.1055/s-1996-5615
  1. Antitumor-promoting Activity of Canventol and its Synthetic Analogs Through Inhibition of Protein Isoprenylation
    Komori, A; Okabe, S.; Suganuma, M.; Kerr, M. A.; Buschpetersen, J.; Oh, L. M.; Zhuo, J. C.; Kannangara, G. S. K.; Zou, X. L.; Tius, M. A.; Fujiki, H. Cancer Science (Formerly Jpn. J. Cancer Res.), 1996, 87, 875-881. DOI: 10.1111/j.1349-7006.1996.tb02114.x
  1. Synthesis of Novel Heterocycles Related to the Dynemycin A Ring Skeleton
    Nicolaou, K. C.; Gross, J. L.; Kerr, M. A. J. Heterocyclic Chem. 1996, 33, 735-746. DOI: 10.1002/jhet.5570330336
  1. The High Pressure Diels-Alder Reactions of an Acylated Quinone Imine Ketal: A 2-Aminobenzyne Equivalent
    M. A. Kerr, Synlett, 1995, 11, 1165-1167. 10.1055/s-1995-5214
  1. A Mild and Efficient Method for the Synthesis of Anilines from Nitroarenes
    Boothroyd, S. R.; Kerr, M. A. Tetrahedron Lett. 1995, 36, 2411-2414. DOI: 10.1016/0040-4039(95)00316-5
  1. Synthesis of the Anthraquinone Framework of Dynemicin A
    Nicolaou, K. C.; Gross, J. L.; Kerr, M. A.; Lemus, R. H.; Ikeda, K.; Ohe, K. Angew. Chem. Int. Ed 1994, 33, 781-783. DOI: 10.1002/anie.199407811
  1. Design, Synthesis and Biological Activity of Protaxols
    Nicolaou K. C.; Riemer C.; Kerr M. A.; Rideout D.; Wrasidlo W. Nature, 1993, 364, 464-466. DOI: 10.1038/364464a0
  1. Halogenated Cannabinoid Synthesis
    Tius, M. A.; Kannangara, G. S. K.; Kerr, M. A.; Grace, K. J. S. Tetrahedron, 1993, 49, 3291-3304. DOI: 10.1016/S0040-4020(01)90158-9
  1. A Novel Approach to the Synthesis of Morphine Alkaloids: The Synthesis of (d,l)-Thebainone-A
    Tius, M. A.; Kerr, M. A. J. Am. Chem. Soc. 1992, 114, 5959-5966. DOI: 10.1021/ja00041a008
  1. A Convenient Synthesis of (-)-11-Nor-Δ9 tetrahydro-cannabinol-9-methanol
    Tius, M. A.; Gu, X-.q.; Kerr, M. A. J. Chem. Soc. Chemical Commun. 1989, 62-63. DOI: 10.1039/C39890000062
  1. A Convenient Synthesis of R-(+)-Perrilaldehyde
    Tius, M. A.; Kerr, M. A. Synthetic Commun. 1988, 18 1905-1911. DOI: 10.1080/00397918808068256